Double-gradient DGGE for optimized detection of DNA point mutations
A novel technique is reported for screening point mutations is genomic DNA: double gradient, denaturing gradient gel electrophoresis (DG-DGGE). Unlike conventional DGGE, which exploits a single gradient of denaturing chemicals (typically urea and formamide) along the migration path to force the two...
Publié dans: | BioTechniques. - 1991. - 22(1997), 2 vom: 31. Feb., Seite 326-30 |
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Auteur principal: | |
Autres auteurs: | , , , |
Format: | Article |
Langue: | English |
Publié: |
1997
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Accès à la collection: | BioTechniques |
Sujets: | Journal Article Research Support, Non-U.S. Gov't CFTR protein, human Cystic Fibrosis Transmembrane Conductance Regulator 126880-72-6 Sodium Dodecyl Sulfate 368GB5141J DNA 9007-49-2 |