Approaches to detection of distantly related proteins by database searches
The searching of protein databases as a method of identifying newly sequenced genes is commonplace in molecular biology laboratories. However, it is a procedure that is not usually formally taught to students, and method cookbooks discuss it only briefly. This article uses a single family of highly...
Publié dans: | BioTechniques. - 1991. - 21(1996), 6 vom: 15. Dez., Seite 1118-22, 1124-5 |
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Auteur principal: | |
Autres auteurs: | , , , , , |
Format: | Article |
Langue: | English |
Publié: |
1996
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Accès à la collection: | BioTechniques |
Sujets: | Journal Article Research Support, Non-U.S. Gov't DNA, Viral Proteins DNA Glycosylases EC 3.2.2.- N-Glycosyl Hydrolases Uracil-DNA Glycosidase |
Résumé: | The searching of protein databases as a method of identifying newly sequenced genes is commonplace in molecular biology laboratories. However, it is a procedure that is not usually formally taught to students, and method cookbooks discuss it only briefly. This article uses a single family of highly diverged uracil-DNA glycosylases, which fall into two distinct groups, to highlight some of the difficulties associated with identification of such proteins by database searching |
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Description: | Date Completed 11.03.1997 Date Revised 28.09.2018 published: Print SWISSPROT: P10186, P12295, P12887, P12888, P20536, P21968, P23379, P32941 Citation Status MEDLINE |
ISSN: | 1940-9818 |