A simple and rapid method for purification of oligodeoxyribonucleoside methylphosphonates

An alternative dimethoxytrityl-on (dmt-on) method is described to purify hydrophobic oligodeoxyribonucleoside methyl-phosphonates (OM) with a phosphodiester linkage at the 5' end, instead of the conventional dmt-off method using a DEAE ion-exchange column. This method is modified from the rever...

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Veröffentlicht in:BioTechniques. - 1993. - 14(1993), 5 vom: 25. Mai, Seite 795-8
1. Verfasser: Lin, S B (VerfasserIn)
Weitere Verfasser: Chang, G W, Teh, G W, Lin, K I, Au, L C
Format: Aufsatz
Sprache:English
Veröffentlicht: 1993
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Journal Article Research Support, Non-U.S. Gov't DNA, Antisense Ethylenediamines Oligodeoxyribonucleotides Organophosphonates ethylenediamine 60V9STC53F
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