Sciatic nerve paralysis following intraarterial chemotherapy for bladder cancer : reports of two cases
Bilateral sciatic nerve paralysis developed in two patients with invasive bladder cancer following intraarterial infusion of cisplatin (CDDP) and 4'-0-tetrahydropyranyladriamycin (THP) as preoperative adjuvant chemotherapy. Balloon catheters were selectively inserted into both internal iliac ar...
| Veröffentlicht in: | Hinyokika kiyo. Acta urologica Japonica. - 1962. - 39(1993), 8 vom: 12. Aug., Seite 743-6 |
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| Weitere Verfasser: | , |
| Format: | Aufsatz |
| Sprache: | Japanese |
| Veröffentlicht: |
1993
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| Zugriff auf das übergeordnete Werk: | Hinyokika kiyo. Acta urologica Japonica |
| Schlagworte: | Case Reports English Abstract Journal Article Doxorubicin 80168379AG pirarubicin D58G680W0G Cisplatin Q20Q21Q62J |
| Zusammenfassung: | Bilateral sciatic nerve paralysis developed in two patients with invasive bladder cancer following intraarterial infusion of cisplatin (CDDP) and 4'-0-tetrahydropyranyladriamycin (THP) as preoperative adjuvant chemotherapy. Balloon catheters were selectively inserted into both internal iliac arteries, and CDDP 100 mg/m2 and THP 40 mg/m2 were administered under balloon occlusion. Pain of lower extremities developed soon after infusion and was gradually followed by paralysis. One patient recovered from paralysis partially after 4 months, but the other patient didn't recover. The use of balloon catheters resulted in an excessive concentration of chemotherapeutic agents with the adverse action on the sciatic nerves |
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| Beschreibung: | Date Completed 20.10.1993 Date Revised 20.11.2014 published: Print Citation Status MEDLINE |
| ISSN: | 0018-1994 |