Introduction of antisense oligonucleotides into cells by permeabilization with streptolysin O

Cellular uptake of antisense oligonucleotides is critical to their ability to inhibit gene expression. In the present study, phosphodiester oligodeoxynucleotides were introduced into cells during brief permeabilization with the pore-forming agent streptolysin O. The extent of antisense inhibition wa...

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Bibliographische Detailangaben
Veröffentlicht in:BioTechniques. - 1991. - 15(1993), 6 vom: 21. Dez., Seite 1016-8, 1020
1. Verfasser: Barry, E L (VerfasserIn)
Weitere Verfasser: Gesek, F A, Friedman, P A
Format: Aufsatz
Sprache:English
Veröffentlicht: 1993
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Research Support, U.S. Gov't, P.H.S. Technical Report Journal Article Bacterial Proteins Calcium Channels Oligonucleotides, Antisense Streptolysins streptolysin O Chlorothiazide 77W477J15H mehr... Calcium SY7Q814VUP