Intravesical bacillus Calmette-Guerin therapy for superficial bladder cancer

Intracavitary instillation of Tokyo 172 strain Bacillas Calmette-Guerin was performed on 39 patients with superficial bladder cancer after contact Nd:YAG laser irradiation for tumors. The BCG group received intravesical instillation of 80 mg BCG at two week intervals for 6 months. Recurrence occurre...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 40(1994), 7 vom: 04. Juli, Seite 575-9
1. Verfasser: Yamada, Y (VerfasserIn)
Weitere Verfasser: Washida, H, Tozawa, K, Honma, H, Kang, K
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1994
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:English Abstract Journal Article BCG Vaccine Tegafur 1548R74NSZ Mitomycin 50SG953SK6 Uracil 56HH86ZVCT
Beschreibung
Zusammenfassung:Intracavitary instillation of Tokyo 172 strain Bacillas Calmette-Guerin was performed on 39 patients with superficial bladder cancer after contact Nd:YAG laser irradiation for tumors. The BCG group received intravesical instillation of 80 mg BCG at two week intervals for 6 months. Recurrence occurred in 7 of the 39 patients. In the 7 recurrent cases instillation of BCG had been discontinued after 2-7 instillations due to bladder irritation, with recurrence seen 6-27 months later. The non-recurrence rate in the group (27 cases) instilled BCG more than seven times was 94.0%. The non-recurrence rate in this group was significantly higher than that in the group (12 cases) with less than six BCG instillations. The non-recurrence rate in the group (26 cases) without BCG therapy was not significantly different from that in the group (12 cases) with less than six BCG instillations. Our findings suggested that frequent (more than seven times) instillation of BCG increased the non-recurrence rate, and that less than six BCG instillations is not significantly effective for preventing the recurrence of superficial bladder cancer
Beschreibung:Date Completed 13.10.1994
Date Revised 21.11.2013
published: Print
Citation Status MEDLINE
ISSN:0018-1994