Quantification of mitochondrial DNA in heteroplasmic fibroblasts with competitive PCR

Quantification of mitochondrial DNA in heteroplasmic fibroblasts with competitive PCR

Kearns-Sayre syndrome (KSS) is a disease with severe clinical symptoms that often arises from a mitochondrial DNA deletion of 4977 bp. Quantification of defective mitochondrial DNA is important since the severity of symptoms in KSS is thought to be related to increased content of abnormal mitochondr...

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Bibliographische Detailangaben
Veröffentlicht in:BioTechniques. - 1988. - 17(1994), 1 vom: 01. Juli, Seite 76-8, 80, 82
1. Verfasser: Wang, H (VerfasserIn)
Weitere Verfasser: Fliegel, L, Cass, C E, Penn, A M, Michalak, M, Weiner, J H, Lemire, B D
Format: Aufsatz
Sprache:English
Veröffentlicht: 1994
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Research Support, Non-U.S. Gov't Technical Report Journal Article DNA, Mitochondrial