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tu |
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231222s1994 xx ||||| 00| ||jpn c |
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|e rakwb
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|a jpn
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| 100 |
1 |
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|a Kawakita, M
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Study on E-cadherin expression in relation to invasion and metastasis in urothelial cancer patients
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| 264 |
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1 |
|c 1994
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|2 rdacarrier
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|a Date Completed 22.03.1995
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|a Date Revised 15.11.2006
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|a published: Print
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|a Citation Status MEDLINE
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| 520 |
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|a E-cadherin expression was investigated in 30 patients with urothelial cancer (bladder; 27, ureter; 2, urethra; 1) by an immunohistochemical method. Twelve out of 22 patients with strong and homogeneous expression of E-cadherin (preserved) had grade 1 tumors, while all 8 patients with heterogeneous, weak and homogeneous, or lost expression of E-cadherin (reduced) had grade 2 or grade 3 tumors. Only 2 out of 22 patients with preserved expression had invasive tumors (> or = pT2), whereas 6 out of 8 patients with reduced expression had invasive tumors (p = 0.002). Three out of 4 patients with metastasis had reduced expression and 2 of them died. These findings suggest that urothelial tumors with reduced expression of E-cadherin have high grade and high stage, and E-cadherin expression could be one of the prognostic factors
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| 650 |
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|a English Abstract
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|a Journal Article
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|a Moroi, S
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kyotani, K
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kakehi, Y
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yoshida, O
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Hinyokika kiyo. Acta urologica Japonica
|d 1962
|g 40(1994), 12 vom: 05. Dez., Seite 1077-80
|w (DE-627)NLM012631779
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|7 nnns
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