Complete response of lung metastasis from bladder cancer by combination chemotherapy with methotrexate, epirubicin and cisplatin : a case report

We report a case of lung metastasis from bladder cancer effectively responding to a combination chemotherapy using methotrexate, epirubicin and cisplatin (MEC therapy). A 78-year-old man with high grade bladder cancer underwent total cystectomy on June 5, 1991. He was pointed out to have an abnormal...

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Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 41(1995), 3 vom: 04. März, Seite 227-30
1. Verfasser: Oouchi, H (VerfasserIn)
Weitere Verfasser: Noguchi, S, Masuda, M, Shuin, T, Kubota, Y, Hosaka, M
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1995
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:Case Reports English Abstract Journal Article Epirubicin 3Z8479ZZ5X Cisplatin Q20Q21Q62J Methotrexate YL5FZ2Y5U1
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520 |a We report a case of lung metastasis from bladder cancer effectively responding to a combination chemotherapy using methotrexate, epirubicin and cisplatin (MEC therapy). A 78-year-old man with high grade bladder cancer underwent total cystectomy on June 5, 1991. He was pointed out to have an abnormal shadow on the plain chest X-ray on August 14, 1992. Computed tomography demonstrated multiple lung metastasis. MEC combination chemotherapy was applied for this case. After 3 courses of MEC therapy, computed tomography showed marked regression of tumor. He has been alive for 12 months with no evidence of disease after chemotherapy. Toxicity of MEC therapy were moderate myelosuppression and mild anorexia and alopecia. These toxicity was adequately tolerable by the 78-year-old patient. This case suggests that MEC therapy is effective against advanced bladder cancer 
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