Rapid and efficient screening for p53 gene mutations by dideoxy fingerprinting

Rapid and efficient screening for p53 gene mutations by dideoxy fingerprinting

Dideoxy fingerprinting (ddF) is an efficient method for detecting single base and other sequence changes in PCR-amplified DNA segments. This screening method is a hybrid between single-strand conformation polymorphism analysis (SSCP) and Sanger dideoxy sequencing. It involves a Sanger sequencing rea...

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Bibliographische Detailangaben
Veröffentlicht in:BioTechniques. - 1991. - 18(1995), 2 vom: 17. Feb., Seite 256-60
1. Verfasser: Blaszyk, H (VerfasserIn)
Weitere Verfasser: Hartmann, A, Schroeder, J J, McGovern, R M, Sommer, S S, Kovach, J S
Format: Aufsatz
Sprache:English
Veröffentlicht: 1995
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Technical Report Journal Article