Rapid and efficient screening for p53 gene mutations by dideoxy fingerprinting

Rapid and efficient screening for p53 gene mutations by dideoxy fingerprinting

Dideoxy fingerprinting (ddF) is an efficient method for detecting single base and other sequence changes in PCR-amplified DNA segments. This screening method is a hybrid between single-strand conformation polymorphism analysis (SSCP) and Sanger dideoxy sequencing. It involves a Sanger sequencing rea...

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Détails bibliographiques
Publié dans:BioTechniques. - 1991. - 18(1995), 2 vom: 17. Feb., Seite 256-60
Auteur principal: Blaszyk, H (Auteur)
Autres auteurs: Hartmann, A, Schroeder, J J, McGovern, R M, Sommer, S S, Kovach, J S
Format: Article
Langue:English
Publié: 1995
Accès à la collection:BioTechniques
Sujets:Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Technical Report Journal Article