Clinical study of allylestrenol (Perselin) on patients with prostatic hypertrophy

The efficacy and safety of allylestrenol were studied in 22 patients with benign prostatic hypertrophy. A 25 mg allylestrenol tablet (Perselin tablet) was administered twice a day. A significant decrease in frequency of nocturnal urination was observed and improvement rates of subjective symptoms, s...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 39(1993), 7 vom: 15. Juli, Seite 679-83
1. Verfasser: Fukuoka, H (VerfasserIn)
Weitere Verfasser: Ishibashi, Y, Shiba, T, Tuchiya, F, Sakanishi, S
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1993
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:English Abstract Journal Article Tablets Allylestrenol I47VB5DZ8O
Beschreibung
Zusammenfassung:The efficacy and safety of allylestrenol were studied in 22 patients with benign prostatic hypertrophy. A 25 mg allylestrenol tablet (Perselin tablet) was administered twice a day. A significant decrease in frequency of nocturnal urination was observed and improvement rates of subjective symptoms, such as sensation of residual urine, delay in start of urination, straining during urination and strength of urinary stream, were 59.1-68.2%. The rate of decrease of maximum area of transverse plane of prostate estimated by transrectal sonography was 13.2% and presumed circle area ratio (PCAR) improved significantly. The incidence of total side effects was 22.7%, whereas a decrease in sexual potency was observed in only 4.5% of the cases. The final global improvement rating of allylestrenol was 72.2% and the rate of usefulness was estimated in 63.6% of the patients. The present findings confirmed that allylestrenol is a useful and safe drug for the treatment of benign prostatic hypertrophy
Beschreibung:Date Completed 24.09.1993
Date Revised 21.11.2013
published: Print
Citation Status MEDLINE
ISSN:0018-1994