Clinical investigation of grade-up superficial bladder cancer

Between January 1977 and December 1993, 249 patients with grade 1 or grade 2 superficial bladder cancer were initially treated at Yokohama City University Hospital. Eighty-six patients (33%) had recurrent tumors after initial resection, and sixteen recurrent cases were so-called grade-up tumors that...

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Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 41(1995), 9 vom: 15. Sept., Seite 659-64
1. Verfasser: Noguchi, S (VerfasserIn)
Weitere Verfasser: Kubota, Y, Masuda, M, Shuin, T, Yao, M, Hosaka, M
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1995
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:English Abstract Journal Article
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520 |a Between January 1977 and December 1993, 249 patients with grade 1 or grade 2 superficial bladder cancer were initially treated at Yokohama City University Hospital. Eighty-six patients (33%) had recurrent tumors after initial resection, and sixteen recurrent cases were so-called grade-up tumors that is, grade 3 originating from grade 1 or grade 2 tumor. The morphology of the grade-up tumors mostly showed non-papillary and invasive type. Positivity for urinary cytology of grade-up tumors was 88%. The five-year survival rate of the patients with grade-up tumors was 85% after initial resection of grade-up patients and 48% after treatment of grade-up tumors. The five-year survival rate of the patients with grade-up tumors who were treated by total cystectomy was 72%, whereas that in the patients who were treated by bladder preservation therapy showed a 13% five-year survival rate and all of the six patients died of cancer during the six-year follow-up period. These findings suggest that patients who have grade up tumors should be treated by radical treatment with radical cystectomy 
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700 1 |a Masuda, M  |e verfasserin  |4 aut 
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700 1 |a Yao, M  |e verfasserin  |4 aut 
700 1 |a Hosaka, M  |e verfasserin  |4 aut 
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