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231222s1980 xx ||||| 00| ||eng c |
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|a pubmed24n0247.xml
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|a (NLM)7433479
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|a DE-627
|b ger
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|e rakwb
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|a eng
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|a Barber, J H
|e verfasserin
|4 aut
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|a Intermittent claudication
|b a controlled study in parallel time of the short-term and long-term effects of cinnarizine
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|c 1980
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|a Band
|b nc
|2 rdacarrier
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|a Date Completed 16.01.1981
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|a Date Revised 21.11.2013
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|a published: Print
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|a Citation Status MEDLINE
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|a In a group of 45 patients with mild to moderately severe claudication studied over the same 4-month period, cinnarizine administration (75 mg 3-times daily) was associated with a greater than 20% improvement in walking distance in 65% of the patients, who derived significantly more benefit than the 30% of placebo responders. The mean improvement in walking distance was 11% for the placebo group compared to 142% for cinnarizine-treated patients. An open 12-month follow-up showed that improvements in walking distance with cinnarizine were maintained in all 12 patients, whereas in the 10 control patients only 10% reported improvement. Objectively, significant plethysmographic improvements were detected only for the cinnarizine-treated patients and shown by an increase in arterial flow-pressure dynamics of the lower limbs
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|a Clinical Trial
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|a Journal Article
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|a Randomized Controlled Trial
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|a Piperazines
|2 NLM
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|a Cinnarizine
|2 NLM
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|a 3DI2E1X18L
|2 NLM
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1 |
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|a Reuter, C A
|e verfasserin
|4 aut
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1 |
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|a Jageneau, A H
|e verfasserin
|4 aut
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1 |
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|a Loots, W
|e verfasserin
|4 aut
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773 |
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|i Enthalten in
|t Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC)
|d 1995
|g 2(1980), 6 vom: 08., Seite 401-7
|w (DE-627)NLM023961570
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