Prophylactic and chemotherapeutic efficacy of pivmecillinam (PMPC) against infections after TUR-P and prostatectomy

The prophylactic and chemotherapeutic efficacy of PMPC against infections after TUR-P has been investigated. Bacteriological evaluation: PMPC , 200-300 mg/day for 2-12 weeks, was administered to 49 patients, who had over 10(3)CFU/ml of microorganisms after CET or CEC treatment for 3-7 days. The erad...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 29(1983), 2 vom: 30. Feb., Seite 245-53
1. Verfasser: Maru, A (VerfasserIn)
Weitere Verfasser: Mitsuhashi, K, Shiba, T, Ohashi, N, Fujieda, J, Nishida, T, Okoshi, R, Kusakai, Y, Amino, I, Kaneda, T
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1983
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:English Abstract Journal Article Amdinocillin Pivoxil 1WAM1OQ30B Penicillanic Acid 87-53-6
LEADER 01000caa a22002652 4500
001 NLM061805084
003 DE-627
005 20250128073501.0
007 tu
008 231221s1983 xx ||||| 00| ||jpn c
028 5 2 |a pubmed25n0206.xml 
035 |a (DE-627)NLM061805084 
035 |a (NLM)6203380 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a jpn 
100 1 |a Maru, A  |e verfasserin  |4 aut 
245 1 0 |a Prophylactic and chemotherapeutic efficacy of pivmecillinam (PMPC) against infections after TUR-P and prostatectomy 
264 1 |c 1983 
336 |a Text  |b txt  |2 rdacontent 
337 |a ohne Hilfsmittel zu benutzen  |b n  |2 rdamedia 
338 |a Band  |b nc  |2 rdacarrier 
500 |a Date Completed 20.07.1984 
500 |a Date Revised 21.11.2013 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a The prophylactic and chemotherapeutic efficacy of PMPC against infections after TUR-P has been investigated. Bacteriological evaluation: PMPC , 200-300 mg/day for 2-12 weeks, was administered to 49 patients, who had over 10(3)CFU/ml of microorganisms after CET or CEC treatment for 3-7 days. The eradication rate of microorganisms was 40.8% after 2 weeks, 52.2% after 4 weeks, 64.1% after 6 weeks, 65.0% after 8 weeks and 70.6% after 12 weeks. Effectiveness on pyuria : The improvement rate of pyuria against 59 patients who had over 10(5)/hpf of pyuria , was 15.3% after 2 weeks, 16.4% after 4 weeks, 25.4% after 6 weeks, 58.5% after 8 weeks, 72.7% after 10 weeks and 75.0% after 12 weeks. Overall clinical efficacy on PMPC was examined in 26 patients. The results of efficacy were 27.3% after 2 weeks, 48.0% after 4 weeks, 50.0% after 6 weeks, 69.2% after 8 weeks, 75.0% after 10 weeks and 77.0% after 12 weeks. The clinical response was evaluated according to a criterion for clinical evaluation of antimicrobial agent on chronic complicated UTI proposed by UTI committee in Japan. No severe adverse effect including allergic reaction was found. Following administration of PMPC , three patients experienced adverse gastric reactions, and drug administration was discontinued at week 6 or 8. PMPC was effective as a prophylactic chemotherapeutic drug against infections after TUR-P and prostatectomy 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 7 |a Amdinocillin Pivoxil  |2 NLM 
650 7 |a 1WAM1OQ30B  |2 NLM 
650 7 |a Penicillanic Acid  |2 NLM 
650 7 |a 87-53-6  |2 NLM 
700 1 |a Mitsuhashi, K  |e verfasserin  |4 aut 
700 1 |a Shiba, T  |e verfasserin  |4 aut 
700 1 |a Ohashi, N  |e verfasserin  |4 aut 
700 1 |a Fujieda, J  |e verfasserin  |4 aut 
700 1 |a Nishida, T  |e verfasserin  |4 aut 
700 1 |a Okoshi, R  |e verfasserin  |4 aut 
700 1 |a Kusakai, Y  |e verfasserin  |4 aut 
700 1 |a Amino, I  |e verfasserin  |4 aut 
700 1 |a Kaneda, T  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Hinyokika kiyo. Acta urologica Japonica  |d 1962  |g 29(1983), 2 vom: 30. Feb., Seite 245-53  |w (DE-627)NLM012631779  |x 0018-1994  |7 nnns 
773 1 8 |g volume:29  |g year:1983  |g number:2  |g day:30  |g month:02  |g pages:245-53 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_20 
912 |a GBV_ILN_22 
912 |a GBV_ILN_40 
912 |a GBV_ILN_60 
912 |a GBV_ILN_72 
912 |a GBV_ILN_120 
912 |a GBV_ILN_350 
912 |a GBV_ILN_2001 
912 |a GBV_ILN_2003 
912 |a GBV_ILN_2005 
912 |a GBV_ILN_2006 
912 |a GBV_ILN_2008 
912 |a GBV_ILN_2010 
912 |a GBV_ILN_2012 
912 |a GBV_ILN_2018 
951 |a AR 
952 |d 29  |j 1983  |e 2  |b 30  |c 02  |h 245-53