Beta-thromboglobulin and platelet factor 4 plasma levels during haemodialysis : effect of indobufen

The effect of a single dose of indobufen (100 mg i.v.) on the release of beta-thromboglobulin and of the platelet factor 4 was investigated during dialysis in 20 uraemic subjects by a within-subjects, single-blind, indobufen versus placebo study. Plasma levels were measured in baseline conditions an...

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Veröffentlicht in:Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC). - 1995. - 3(1982), 2 vom: 27., Seite 127-32
1. Verfasser: Pogliani, E M (VerfasserIn)
Weitere Verfasser: Colombi, M, Cristoforetti, G, Valenti, G, Miradoli, R, Buccianti, G
Format: Aufsatz
Sprache:English
Veröffentlicht: 1982
Zugriff auf das übergeordnete Werk:Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC)
Schlagworte:Clinical Trial Controlled Clinical Trial Journal Article Beta-Globulins Blood Coagulation Factors Indoles Isoindoles Phenylbutyrates beta-Thromboglobulin Platelet Factor 4 mehr... 37270-94-3 indobufen 6T9949G4LZ
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245 1 0 |a Beta-thromboglobulin and platelet factor 4 plasma levels during haemodialysis  |b effect of indobufen 
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500 |a Date Completed 17.09.1982 
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520 |a The effect of a single dose of indobufen (100 mg i.v.) on the release of beta-thromboglobulin and of the platelet factor 4 was investigated during dialysis in 20 uraemic subjects by a within-subjects, single-blind, indobufen versus placebo study. Plasma levels were measured in baseline conditions and 15, 30, 60, 120 and 240 minutes after the beginning of dialysis. Pre-treatment with indobufen clearly inhibited beta-TG and PF 4 output. The difference from placebo was highly significant (p less than 0.01) from the 30-minute control up to the end of dialysis. No changes in platelet count before and after dialysis were observed 
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700 1 |a Valenti, G  |e verfasserin  |4 aut 
700 1 |a Miradoli, R  |e verfasserin  |4 aut 
700 1 |a Buccianti, G  |e verfasserin  |4 aut 
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