Bromazepam ('Lexotanil') compared with placebo : a double-blind, crossover study
A double-blind, crossover study was carried out in 126 out-patients, most of them neurotics, to compare the efficacy and tolerance of bromazepam and placebo. Patients received either 6 mg bromazepam or placebo daily for 3 weeks and were then crossed over to the alternative treatment for a further 3...
| Veröffentlicht in: | Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC). - 1995. - 4(1984), 1 vom: 22., Seite 13-20 |
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| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
1984
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| Zugriff auf das übergeordnete Werk: | Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC) |
| Schlagworte: | Clinical Trial Comparative Study Journal Article Randomized Controlled Trial Anti-Anxiety Agents Bromazepam X015L14V0O |
| Zusammenfassung: | A double-blind, crossover study was carried out in 126 out-patients, most of them neurotics, to compare the efficacy and tolerance of bromazepam and placebo. Patients received either 6 mg bromazepam or placebo daily for 3 weeks and were then crossed over to the alternative treatment for a further 3 weeks. Treatment sequence was randomized. Clinical ratings of the severity of individual symptoms and the Hamilton Anxiety Rating Scale were used to measure response to treatment at the end of each period. During the first period, both bromazepam and placebo produced improvement and there was no statistically significant difference between the two groups. During the second period after crossover, however, significantly better results were achieved in patients on bromazepam than those on placebo. The incidence of side-effects, mainly drowsiness, was similar with bromazepam and placebo |
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| Beschreibung: | Date Completed 04.01.1985 Date Revised 21.11.2013 published: Print Citation Status MEDLINE |