Clinical experience of norfloxacin in urinary tract infection

Norfloxacin (NFLX) was administered to outpatients and inpatients with urinary tract infections at our department. Clinical efficacy and safety were evaluated in 50 patients by the criteria for evaluation of clinical efficacy of antimicrobial agents on urinary tract infection. Overall clinical effic...

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Bibliographische Detailangaben
Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 31(1985), 8 vom: 15. Aug., Seite 1501-17
1. Verfasser: Banya, Y (VerfasserIn)
Weitere Verfasser: Funaki, H, Takagane, H, Tanji, S, Abe, T, Aoki, H, Kubo, T, Ohori, T
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1985
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:English Abstract Journal Article Norfloxacin N0F8P22L1P
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520 |a Norfloxacin (NFLX) was administered to outpatients and inpatients with urinary tract infections at our department. Clinical efficacy and safety were evaluated in 50 patients by the criteria for evaluation of clinical efficacy of antimicrobial agents on urinary tract infection. Overall clinical efficacy for 17 cases with acute simple cystitis was excellent in 13 cases, moderate in 4 cases with an effectiveness rate of 100%. The overall clinical efficacy for 33 cases with chronic complicated UTI was excellent in 18 cases, moderate in 6 cases and poor in 9 cases with an effectiveness rate of 73%. The eradication rate of 21 strains from acute simple cystitis patients was 100%. Forty four out of 60 strains from chronic complicated UTI patients were eradicated and the eradication rate was 73%. Neither subjective nor objective adverse reactions were observed in 50 patients. Abnormal changes in laboratory tests were found in 8 patients, but were probably not related to NFLX administration. Judging from these results, NFLX is considered to be an effective and safe antibacterial for the treatment of UTI 
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700 1 |a Takagane, H  |e verfasserin  |4 aut 
700 1 |a Tanji, S  |e verfasserin  |4 aut 
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700 1 |a Aoki, H  |e verfasserin  |4 aut 
700 1 |a Kubo, T  |e verfasserin  |4 aut 
700 1 |a Ohori, T  |e verfasserin  |4 aut 
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