Relationship between plasma and stimulated-saliva concentrations of theophylline in asthmatic children

The trough steady-state concentration of theophylline in plasma and stimulated saliva of 12 asthmatic children receiving an oral slow-release theophylline preparation was determined after 1 week of treatment. Plasma theophylline concentration ranged from 3.6 to 10.8 microgram/ml and saliva concentra...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC). - 1995. - 4(1985), 5 vom: 23., Seite 285-7
1. Verfasser: Krivoy, N (VerfasserIn)
Weitere Verfasser: Zinman, P, Hoffer, E, Teitelman, U, Rubin, A
Format: Aufsatz
Sprache:English
Veröffentlicht: 1985
Zugriff auf das übergeordnete Werk:Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC)
Schlagworte:Journal Article Theophylline C137DTR5RG
LEADER 01000naa a22002652 4500
001 NLM040515656
003 DE-627
005 20231221151248.0
007 tu
008 231221s1985 xx ||||| 00| ||eng c
028 5 2 |a pubmed24n0135.xml 
035 |a (DE-627)NLM040515656 
035 |a (NLM)4070321 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Krivoy, N  |e verfasserin  |4 aut 
245 1 0 |a Relationship between plasma and stimulated-saliva concentrations of theophylline in asthmatic children 
264 1 |c 1985 
336 |a Text  |b txt  |2 rdacontent 
337 |a ohne Hilfsmittel zu benutzen  |b n  |2 rdamedia 
338 |a Band  |b nc  |2 rdacarrier 
500 |a Date Completed 30.12.1985 
500 |a Date Revised 21.11.2013 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a The trough steady-state concentration of theophylline in plasma and stimulated saliva of 12 asthmatic children receiving an oral slow-release theophylline preparation was determined after 1 week of treatment. Plasma theophylline concentration ranged from 3.6 to 10.8 microgram/ml and saliva concentration ranged from 3.2 to 7.0 microgram/ml. There was an excellent linear relationship between theophylline concentration in plasma and stimulated saliva (r=0.89, p is less than 0.001). These observations suggest that theophylline therapy could be monitored routinely using stimulated saliva. This may be a convenient, painless and non-invasive alternative for routine monitoring of theophylline levels in asthmatic children 
650 4 |a Journal Article 
650 7 |a Theophylline  |2 NLM 
650 7 |a C137DTR5RG  |2 NLM 
700 1 |a Zinman, P  |e verfasserin  |4 aut 
700 1 |a Hoffer, E  |e verfasserin  |4 aut 
700 1 |a Teitelman, U  |e verfasserin  |4 aut 
700 1 |a Rubin, A  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC)  |d 1995  |g 4(1985), 5 vom: 23., Seite 285-7  |w (DE-627)NLM023961570 
773 1 8 |g volume:4  |g year:1985  |g number:5  |g day:23  |g pages:285-7 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_11 
912 |a GBV_ILN_22 
912 |a GBV_ILN_24 
912 |a GBV_ILN_31 
912 |a GBV_ILN_39 
912 |a GBV_ILN_40 
912 |a GBV_ILN_72 
912 |a GBV_ILN_120 
912 |a GBV_ILN_121 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 4  |j 1985  |e 5  |b 23  |h 285-7