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01000naa a22002652 4500 |
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NLM038879263 |
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DE-627 |
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20231221143942.0 |
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tu |
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231221s1985 xx ||||| 00| ||eng c |
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|a pubmed24n0130.xml
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|a (DE-627)NLM038879263
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|a (NLM)3906673
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Roussan, M
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Baclofen versus diazepam for the treatment of spasticity and long-term follow-up of baclofen therapy
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| 264 |
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1 |
|c 1985
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 30.12.1985
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| 500 |
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|a Date Revised 21.11.2013
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|a published: Print
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|a Citation Status MEDLINE
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|a Baclofen (25 to 60 mg per day) and diazepam (10 to 40 mg per day) were evaluated for spasticity reduction in a double-blind, crossover study in 13 patients over a period of 19 weeks. Both drugs produced overall improvement and there was no significant difference in preference for one or other treatment. Side-effects, especially excessive daytime sedation, were more common in the diazepam group. In a companion baclofen long-term study, 18 spastic patients were treated with baclofen for an average of 4 years. Baclofen discontinuation in this group resulted in a worsening of spastic signs and symptoms in 16 patients, with no evidence of drug tolerance even after many years of baclofen therapy
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| 650 |
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|a Clinical Trial
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| 650 |
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|a Comparative Study
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| 650 |
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|a Controlled Clinical Trial
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|a Journal Article
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| 650 |
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|a Randomized Controlled Trial
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| 650 |
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|a Research Support, U.S. Gov't, Non-P.H.S.
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| 650 |
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7 |
|a Baclofen
|2 NLM
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| 650 |
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7 |
|a H789N3FKE8
|2 NLM
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| 650 |
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7 |
|a Diazepam
|2 NLM
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| 650 |
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7 |
|a Q3JTX2Q7TU
|2 NLM
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| 700 |
1 |
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|a Terrence, C
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Fromm, G
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC)
|d 1995
|g 4(1985), 5 vom: 23., Seite 278-84
|w (DE-627)NLM023961570
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| 773 |
1 |
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|g volume:4
|g year:1985
|g number:5
|g day:23
|g pages:278-84
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|d 4
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|h 278-84
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