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231221s1986 xx ||||| 00| ||eng c |
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|a pubmed24n0125.xml
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|a (DE-627)NLM037449079
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|a (NLM)3763653
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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1 |
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|a Ingerslev, J
|e verfasserin
|4 aut
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|a Pentoxifylline does not interfere with stable coumarin anticoagulant therapy
|b a clinical study
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|c 1986
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|a Band
|b nc
|2 rdacarrier
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|a Date Completed 17.11.1986
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|a Date Revised 21.11.2013
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|a published: Print
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|a Citation Status MEDLINE
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|a A study was undertaken to investigate the possible interaction between pentoxifylline and coumarin. Ten patients on a previously stable anticoagulant treatment were investigated twice prior to, then 13 and 27 days after initiation of treatment with 1600 mg pentoxifylline daily. Coumarin therapy was continued in unaltered dosage. Parameters recorded were: bleeding time, platelet count, platelet adhesivity, spontaneous and collagen-induced platelet aggregation, activated partial thromboplastin time, prothrombin time, prothrombin-proconvertin activity, plasminogen activator and fibrin(ogen) degradation products. Platelet aggregation studies revealed a slightly higher sensitivity to collagen in 2 patients compared to pre-treatment values and in 1 patient the tendency to spontaneous aggregation was slightly increased after treatment. No other single test result changed significantly from premedication baseline values
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|a Journal Article
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|a 4-Hydroxycoumarins
|2 NLM
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|a Blood Coagulation Factors
|2 NLM
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|a Theobromine
|2 NLM
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|a OBD445WZ5P
|2 NLM
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|a Phenprocoumon
|2 NLM
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|a Q08SIO485D
|2 NLM
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|a Pentoxifylline
|2 NLM
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|a SD6QCT3TSU
|2 NLM
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1 |
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|a Mouritzen, C
|e verfasserin
|4 aut
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1 |
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|a Stenbjerg, S
|e verfasserin
|4 aut
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773 |
0 |
8 |
|i Enthalten in
|t Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC)
|d 1995
|g 4(1986), 9 vom: 15., Seite 595-600
|w (DE-627)NLM023961570
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|g volume:4
|g year:1986
|g number:9
|g day:15
|g pages:595-600
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|a AR
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|d 4
|j 1986
|e 9
|b 15
|h 595-600
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