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tu |
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231221s1987 xx ||||| 00| ||eng c |
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|a (NLM)3499769
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|a DE-627
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|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Morita, T
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Evaluation of lymphocyte subpopulations in patients with bladder cancer
|b a study with monoclonal antibodies
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| 264 |
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1 |
|c 1987
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 11.12.1987
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| 500 |
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|a Date Revised 19.11.2015
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| 500 |
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|a published: Print
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| 500 |
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|a Citation Status MEDLINE
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| 520 |
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|a Peripheral blood lymphocyte subpopulations of 47 patients with bladder cancer were analyzed using monoclonal antibodies (OKT3, OKT4, OKT8 and OKIa7). Thirty five patients were untreated, and 12 were treated, disease-free patients. In untreated patients, the number of total lymphocytes and the percentage of OKT3+ cells decreased. Among the OKT3+ T cell population, the percentage of OKT4+ cells tended to decrease significantly, whereas the percentage of OKT8+ cells rather increased, resulting in the decrease of the OKT4+/OKT8+ ratio. These tendencies became more evident as the stage advanced. In treated, disease-free patients, no such characteristic changes were observed and the lymphocyte subpopulation apparently fell into the normal range. Furthermore, the retrospective study clearly indicated that the patients with a lower OKT4+/OKT8+ ratio showed a higher recurrence rate within a year. Analysis of peripheral blood lymphocyte subpopulations thus appears to be useful in the follow-up of bladder cancer patients, especially those with superficial tumors
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| 650 |
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|a Journal Article
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| 650 |
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7 |
|a Antibodies, Monoclonal
|2 NLM
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| 650 |
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7 |
|a Antigens, Surface
|2 NLM
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| 700 |
1 |
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|a Yonese, Y
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Minato, N
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Hinyokika kiyo. Acta urologica Japonica
|d 1962
|g 33(1987), 6 vom: 01. Juni, Seite 838-43
|w (DE-627)NLM012631779
|x 0018-1994
|7 nnns
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| 773 |
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