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231221s1988 xx ||||| 00| ||jpn c |
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|a pubmed25n0112.xml
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|a (NLM)3376793
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a jpn
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| 100 |
1 |
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|a Akakura, K
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Trends in patterns of care for prostatic cancer in Japan
|b statistics of 9 institutions for 5 years
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| 264 |
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1 |
|c 1988
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 24.06.1988
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| 500 |
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|a Date Revised 15.11.2006
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|a published: Print
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|a Citation Status MEDLINE
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| 520 |
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|a Five hundred and sixty-five patients with prostatic cancer, who first visited 9 institutions in Japan between 1981 and 1985, were analyzed. The peak of age distribution was in the seventies. As clinical symptoms, disturbance on micturition was the most frequent and pain caused by metastasis was a complaint in approximately one tenth of the cases. Alkaline phosphatase measurement, prostatic biopsy, intravenous pyelography, bone scintigraphy, cystourethrography, and measurements of serum prostatic acid phosphatase and serum acid phosphatase were performed on more than 80% of the patients. The clinical stage was stage A1 in 6.2%, A2 in 3.7%, B in 14.9%, C in 20.7%, D1 in 7.4%, and D2 in 43.7%. According to the histological grade, well, moderately and poorly differentiated adenocarcinoma were observed in 20.4, 33.3 and 32.7%, respectively. Increased ratio of high grade to low grade was noticed in the lower age group as well as in the advanced stage. In this series, endocrine therapy was still accepted in most of the patients. Almost all were treated with hormonal medication and half of them had undergone bilateral orchiectomy. Surgery, radiation, chemotherapy or multidisciplinary therapy were attempted judging from the clinical stage and histological grade. However, old age restricted the therapeutic modality. Actuarial survival rate at 5 years for stage A1, A2, B, C, D1 and D2 was 89.2, 66.1, 72.7, 51.0, 47.5 and 28.0%, respectively. In the patients with stage D2, the 5-year actuarial rate of poorly differentiated adenocarcinoma was lower than that of well or moderately differentiated adenocarcinoma, even though more intensive therapy was given to the former
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| 650 |
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|a English Abstract
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| 650 |
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|a Journal Article
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| 650 |
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|a Research Support, Non-U.S. Gov't
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| 700 |
1 |
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|a Isaka, S
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Fuse, H
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Akimoto, S
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Imai, K
|e verfasserin
|4 aut
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| 700 |
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|a Yamanaka, H
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Akaza, H
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Niijima, T
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Moriyama, N
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kawabe, K
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Hinyokika kiyo. Acta urologica Japonica
|d 1962
|g 34(1988), 1 vom: 15. Jan., Seite 123-9
|w (DE-627)NLM012631779
|x 0018-1994
|7 nnns
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| 773 |
1 |
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|g volume:34
|g year:1988
|g number:1
|g day:15
|g month:01
|g pages:123-9
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| 912 |
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| 951 |
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|a AR
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| 952 |
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|d 34
|j 1988
|e 1
|b 15
|c 01
|h 123-9
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