Treatment of prostatic cancer with slow-release formulation of luteinizing hormone releasing hormone (LH-RH) analog

A slow-release formulation of the luteinizing hormone releasing hormone (LH-RH)analog(TAP-144-SR) was administered in 6 cases of prostatic cancer. Five were untreated cases, 3 of moderately-differentiated and 2 of poorly-differentiated cancers (four D2 and one C, NX), the other (D2) was under contro...

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Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 34(1988), 3 vom: 15. März, Seite 555-60
1. Verfasser: Fuse, H (VerfasserIn)
Weitere Verfasser: Akimoto, S, Akakura, K, Shimazaki, J, Murakami, S
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1988
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:English Abstract Journal Article Antineoplastic Agents Delayed-Action Preparations Gonadotropin-Releasing Hormone 33515-09-2 Testosterone 3XMK78S47O Luteinizing Hormone 9002-67-9 mehr... Follicle Stimulating Hormone 9002-68-0 Acid Phosphatase EC 3.1.3.2 Leuprolide EFY6W0M8TG
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245 1 0 |a Treatment of prostatic cancer with slow-release formulation of luteinizing hormone releasing hormone (LH-RH) analog 
264 1 |c 1988 
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500 |a Date Completed 11.08.1988 
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520 |a A slow-release formulation of the luteinizing hormone releasing hormone (LH-RH)analog(TAP-144-SR) was administered in 6 cases of prostatic cancer. Five were untreated cases, 3 of moderately-differentiated and 2 of poorly-differentiated cancers (four D2 and one C, NX), the other (D2) was under control by another LH-RH analog. The plasma level of luteinizing hormone and follicle stimulating hormone fell below normal, and the plasma testosterone was less than 1 ng/ml by four weeks after start of treatment. According to the National Prostatic Cancer Project Criteria, 2 of the untreated cases showed a partial response and 3 of the untreated ones showed a stable response, one of which underwent transurethral resection later. The pretreated case still continued controlled more than 4 months. No side effect was noticed 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 7 |a Antineoplastic Agents  |2 NLM 
650 7 |a Delayed-Action Preparations  |2 NLM 
650 7 |a Gonadotropin-Releasing Hormone  |2 NLM 
650 7 |a 33515-09-2  |2 NLM 
650 7 |a Testosterone  |2 NLM 
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650 7 |a Acid Phosphatase  |2 NLM 
650 7 |a EC 3.1.3.2  |2 NLM 
650 7 |a Leuprolide  |2 NLM 
650 7 |a EFY6W0M8TG  |2 NLM 
700 1 |a Akimoto, S  |e verfasserin  |4 aut 
700 1 |a Akakura, K  |e verfasserin  |4 aut 
700 1 |a Shimazaki, J  |e verfasserin  |4 aut 
700 1 |a Murakami, S  |e verfasserin  |4 aut 
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