Uromodulin : an immunoregulatory glycoprotein isolated from pregnancy urine that binds to and regulates the activity of interleukin 1

Uromodulin is an 85 kilodalton glycoprotein originally isolated from human pregnancy which has been shown to inhibit antigen specific T cell responses to recall antigens such as tetanus toxoid. We have also found that uromodulin is a high affinity ligand for interleukin 1 and is able to regulate the...

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Détails bibliographiques
Publié dans:Malignant potential of aneuploid pancreatic endocrine tumours. - 1993. - 11(1986), 3 vom: 25. Juli, Seite 89-93
Auteur principal: Muchmore, A V (Auteur)
Format: Article
Langue:English
Publié: 1986
Accès à la collection:Malignant potential of aneuploid pancreatic endocrine tumours
Sujets:Journal Article Adjuvants, Immunologic Interleukin-1 Mucoproteins Pregnancy Proteins Receptors, Immunologic Receptors, Interleukin-2 UMOD protein, human Uromodulin