An open assessment of three different treatment regimens of itraconazole for the management of vaginal candidosis

An assessment was carried out in 59 women with proven vaginal candidosis to compare the efficacy and tolerance of itraconazole used in three different treatment regimens. Patients were allocated at random to receive a single oral dose of 200 mg itraconazole for 1, 2 or 3 days. They were reassessed 1...

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Veröffentlicht in:Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC). - 1995. - 5(1988), 3 vom: 05., Seite 189-92
1. Verfasser: Silva Cruz, A (VerfasserIn)
Weitere Verfasser: Andrade, L, Oliveira, J E, Sobral, J L
Format: Aufsatz
Sprache:English
Veröffentlicht: 1988
Zugriff auf das übergeordnete Werk:Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC)
Schlagworte:Clinical Trial Comparative Study Journal Article Randomized Controlled Trial Antifungal Agents Itraconazole 304NUG5GF4 Ketoconazole R9400W927I
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245 1 3 |a An open assessment of three different treatment regimens of itraconazole for the management of vaginal candidosis 
264 1 |c 1988 
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520 |a An assessment was carried out in 59 women with proven vaginal candidosis to compare the efficacy and tolerance of itraconazole used in three different treatment regimens. Patients were allocated at random to receive a single oral dose of 200 mg itraconazole for 1, 2 or 3 days. They were reassessed 1 week and 4 weeks after treatment for remission of clinical signs and symptoms and repeat mycological investigations. All three regimens yielded successful clinical results, global evaluation at 4 weeks showing complete remission in 100% (5/5), 81.5% (25/27) and 92.3% (24/26) of patients, respectively. One patient (on 2-day treatment) required alternative treatment before the 4-week assessment. Minor gastric side-effects were reported by a few patients on the 2-day and 3-day treatment regimens; these resolved spontaneously 
650 4 |a Clinical Trial 
650 4 |a Comparative Study 
650 4 |a Journal Article 
650 4 |a Randomized Controlled Trial 
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650 7 |a Itraconazole  |2 NLM 
650 7 |a 304NUG5GF4  |2 NLM 
650 7 |a Ketoconazole  |2 NLM 
650 7 |a R9400W927I  |2 NLM 
700 1 |a Andrade, L  |e verfasserin  |4 aut 
700 1 |a Oliveira, J E  |e verfasserin  |4 aut 
700 1 |a Sobral, J L  |e verfasserin  |4 aut 
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