The study on cell surface antigens in epithelial tumor of the upper urinary tract ABH-isoantigen and Thomsen-Friedenreich antigen

The study on cell surface antigens in epithelial tumor of the upper urinary tract : ABH-isoantigen and Thomsen-Friedenreich antigen

ABH-isoantigen (ABH-Ag) and Thomsen-Friedenreich antigen (T-Ag) were investigated by the Avidin-Biotin-Peroxidase Complex (ABC) method on 47 patients with epithelial tumor of the upper urinary tract (all patients underwent nephroureterectomy including the cuff of the bladder; 30 patients were diagno...

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Bibliographische Detailangaben
Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 35(1989), 6 vom: 12. Juni, Seite 949-54
1. Verfasser: Fukatsu, H (VerfasserIn)
Weitere Verfasser: Nonomura, H, Miyagawa, Y, Waki, M, Hatano, Y, Hiraiwa, S, Muramatsu, T, Nishikawa, E, Yamada, Y, Satoh, T
Format: Aufsatz
Sprache:English
Veröffentlicht: 1989
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:Journal Article ABO Blood-Group System Antigens, Tumor-Associated, Carbohydrate Disaccharides Isoantigens Thomsen-Friedenreich antigen 3554-90-3
Beschreibung
Zusammenfassung:ABH-isoantigen (ABH-Ag) and Thomsen-Friedenreich antigen (T-Ag) were investigated by the Avidin-Biotin-Peroxidase Complex (ABC) method on 47 patients with epithelial tumor of the upper urinary tract (all patients underwent nephroureterectomy including the cuff of the bladder; 30 patients were diagnosed as transitional cell carcinoma of renal pelvis and 17 ureteral organs). The correlations between ABC expression for ABH-Ag and T-Ag with histological grade, stage and prognosis (5 year survival rate) were studied. A correlation was observed between grade (p less than 0.05) and deletion of the antigenicity of ABH-Ag, but no correlation was evident with stage and prognosis. A high correlation was evident, however, between grade (p less than 0.01), stage (p less than 0.01) and prognosis (p less than 0.01) and deletion of the antigenicity of T-Ag. The analysis of ABC expression for ABH-Ag and T-Ag may therefore be valuable for predicting the malignant potential in transitional cell carcinoma of the upper urinary tract. T-Ag determination in particular may provide a useful prognostic probe should it find clinical application
Beschreibung:Date Completed 21.11.1989
Date Revised 05.12.2007
published: Print
Citation Status MEDLINE
ISSN:0018-1994