Ofloxacin concentration in human prostatic tissue after 3 days of administration
The present study was undertaken to evaluate the penetration of ofloxacin into prostatic tissue. Thirty-one patients with benign prostatic hypertrophy were entered in the study. Ofloxacin was administered orally in a dose of 200 mg three times daily for 3 days preoperatively. Blood samples were take...
| Veröffentlicht in: | Hinyokika kiyo. Acta urologica Japonica. - 1962. - 35(1989), 1 vom: 15. Jan., Seite 187-90 |
|---|---|
| 1. Verfasser: | |
| Weitere Verfasser: | |
| Format: | Aufsatz |
| Sprache: | Japanese |
| Veröffentlicht: |
1989
|
| Zugriff auf das übergeordnete Werk: | Hinyokika kiyo. Acta urologica Japonica |
| Schlagworte: | English Abstract Journal Article Ofloxacin A4P49JAZ9H |
| Zusammenfassung: | The present study was undertaken to evaluate the penetration of ofloxacin into prostatic tissue. Thirty-one patients with benign prostatic hypertrophy were entered in the study. Ofloxacin was administered orally in a dose of 200 mg three times daily for 3 days preoperatively. Blood samples were taken simultaneously at the time of tissue sampling. The patients were divided into 2 groups. In group 1, tissue sampling was done about 17 hours after the final drug administration. The mean concentration of ofloxacin was 6.88 +/- 3.98 micrograms/g in prostatic tissue and 2.14 +/- 0.81 micrograms/ml in serum. In group 2, sampling was done 5.5 hours after the final administration. The mean concentration of ofloxacin was 6.73 +/- 2.99 micrograms/g in prostatic tissue and 2.90 +/- 1.50 micrograms/ml in serum |
|---|---|
| Beschreibung: | Date Completed 10.07.1989 Date Revised 21.11.2013 published: Print Citation Status MEDLINE |
| ISSN: | 0018-1994 |