Detection of early pregnancy factor in human sera
The rosette inhibition titers (RIT) for sera from 94 women at various stages of gestation were detected with a standardized rosette inhibition test. The results showed that an immunosuppressive substance, named early pregnancy factor (EPF), did exist in the pregnancy sera. We confirmed that the EPF...
| Veröffentlicht in: | American journal of reproductive immunology and microbiology : AJRIM. - 1985. - 13(1987), 1 vom: 15. Jan., Seite 15-8 |
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| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
1987
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| Zugriff auf das übergeordnete Werk: | American journal of reproductive immunology and microbiology : AJRIM |
| Schlagworte: | Journal Article Chaperonin 10 Chorionic Gonadotropin Immunosuppressive Agents Peptides Pregnancy Proteins Suppressor Factors, Immunologic alpha-Fetoproteins early pregnancy factor |
| Zusammenfassung: | The rosette inhibition titers (RIT) for sera from 94 women at various stages of gestation were detected with a standardized rosette inhibition test. The results showed that an immunosuppressive substance, named early pregnancy factor (EPF), did exist in the pregnancy sera. We confirmed that the EPF activity was very high in the early pregnant stage (the mean RIT = 6.30), gradually decreased with the continuance of gestation, and disappeared at 8 weeks before delivery when the mean RIT for sera (less than 4) had fallen in the RIT nonpregnant range. In addition, observations for the EPF dynamic changes before and at varying stages after the induced abortion in 21 pregnant women showed that the mean RIT was 5.9 +/- 0.25 (SE) before the abortion and dropped below 4 (EPF activity could not be detected) at 3-5 days after the abortion |
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| Beschreibung: | Date Completed 11.05.1987 Date Revised 04.04.2017 published: Print Citation Status MEDLINE |
| ISSN: | 8755-8920 |