False-positive elevation of alpha-fetoprotein during induction chemotherapy in patients with testicular cancer

During induction chemotherapy, we experienced the false elevation of the tumor marker alpha-fetoprotein (AFP) in some disseminated testicular cancer patients. We discussed the possibility of the false elevation of the tumor marker AFP and evaluated the relationship between AFP and the markers of liv...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 32(1986), 12 vom: 30. Dez., Seite 1859-66
1. Verfasser: Hida, S (VerfasserIn)
Weitere Verfasser: Kawakita, M, Oishi, K, Okada, Y, Takeuchi, H, Okada, K, Yoshida, O
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1986
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:English Abstract Journal Article alpha-Fetoproteins Bleomycin 11056-06-7 Chlorambucil 18D0SL7309 Dactinomycin 1CC1JFE158 Vinblastine mehr... 5V9KLZ54CY Doxorubicin 80168379AG Cyclophosphamide 8N3DW7272P L-Lactate Dehydrogenase EC 1.1.1.27 Aspartate Aminotransferases EC 2.6.1.1 Alanine Transaminase EC 2.6.1.2 Cisplatin Q20Q21Q62J
Beschreibung
Zusammenfassung:During induction chemotherapy, we experienced the false elevation of the tumor marker alpha-fetoprotein (AFP) in some disseminated testicular cancer patients. We discussed the possibility of the false elevation of the tumor marker AFP and evaluated the relationship between AFP and the markers of liver damage (GOT, GPT, LDH, etc.), the elevation of which were caused by induction chemotherapy of the VAB-6 regimen. We evaluated each variable of the eleven patients with disseminated testicular cancer who had been treated in our hospital between 1979 and 1984. The elevation of each marker of liver damage was induced by the VAB-6 regimen, immediately after the end of each induction chemotherapy but not by other induction chemotherapy regimens. A statistical study confirmed that there was a close correlation between the elevation of AFP and of the markers of liver damage, that is induced frequently by the induction chemotherapy of VAB-6 regimen
Beschreibung:Date Completed 06.04.1987
Date Revised 21.11.2013
published: Print
Citation Status MEDLINE
ISSN:0018-1994