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231221s1985 xx ||||| 00| ||jpn c |
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|e rakwb
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|a jpn
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1 |
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|a Takao, M
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Concentration level of latamoxef sodium (LMOX) in prostatic tissue
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| 264 |
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1 |
|c 1985
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|2 rdacarrier
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| 500 |
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|a Date Completed 06.09.1985
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| 500 |
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|a Date Revised 21.11.2013
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| 500 |
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|a published: Print
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|a Citation Status MEDLINE
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| 520 |
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|a The concentration of latamoxef sodium (LMOX) in serum and prostatic tissue was evaluated. Thirty seven patients with benign prostatic hypertrophy were given 1 g LMOX intravenously prior to prostatectomy. Prostatic tissue and blood were sampled at 1, 2 or 3 hrs after administration of LMOX. The concentration of LMOX in prostatic tissue was 17.4 +/- 3.4 micrograms/g tissue, 11.1 +/- 1.3 microgram/g tissue and 8.9 +/- 1.3 microgram/g tissue 1, 2 and 3 hrs after injection, respectively (mean +/- S.E.). The penetration ratio of LMOX (concentration in tissue/in serum) to prostate was 30-45%. Therefore, the 80% MIC of LMOX is lower than 8 micrograms/ml for most gram negative bacteria, the results suggest that LMOX is very effective against prostatitis caused by these organisms
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| 650 |
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|a English Abstract
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|a Journal Article
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|a Matsuzaki, S
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|a Ao, T
|e verfasserin
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| 700 |
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|a Nagakura, K
|e verfasserin
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|i Enthalten in
|t Hinyokika kiyo. Acta urologica Japonica
|d 1962
|g 31(1985), 3 vom: 15. März, Seite 539-43
|w (DE-627)NLM012631779
|x 0018-1994
|7 nnas
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| 773 |
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|g volume:31
|g year:1985
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|g month:03
|g pages:539-43
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