Reactivation of prostatic cancer and chemotherapy in reactivated prostatic cancer

From January, 1960 to March, 1984, we studied 65 cases of prostatic cancer resistant to endocrine therapy. Treatment with ifosfamide or combination chemotherapy with vincristine, ifosfamide and peplomycin was performed in some of the 65 cases above mentioned. More cases were systemic reactivation th...

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Détails bibliographiques
Publié dans:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 31(1985), 2 vom: 01. Feb., Seite 281-7
Auteur principal: Fuse, H (Auteur)
Autres auteurs: Ando, K, Hara, S, Zama, S, Shimazaki, J
Format: Article
Langue:Japanese
Publié: 1985
Accès à la collection:Hinyokika kiyo. Acta urologica Japonica
Sujets:Comparative Study English Abstract Journal Article Bleomycin 11056-06-7 Vincristine 5J49Q6B70F Cyclophosphamide 8N3DW7272P Ifosfamide UM20QQM95Y
Description
Résumé:From January, 1960 to March, 1984, we studied 65 cases of prostatic cancer resistant to endocrine therapy. Treatment with ifosfamide or combination chemotherapy with vincristine, ifosfamide and peplomycin was performed in some of the 65 cases above mentioned. More cases were systemic reactivation than local reactivation. Poorly differentiated cancer accounted for the majority of the reactivated cancer. Concerning adjacent effects, treatment with ifosfamide was superior to combination chemotherapy. There was no difference between the distant effects of both chemotherapies. The patients with no effects showed predominance of pathologically low differentiated cell type. The 6-month survival rate of patients with chemotherapy was significantly higher than that of patients with other therapies. Toxicities of chemotherapies were leucopenia, digestive disturbances and falling out of hair. Hematuria and pulmonary fibrosis occurred in some cases
Description:Date Completed 26.07.1985
Date Revised 19.11.2015
published: Print
Citation Status MEDLINE
ISSN:0018-1994