Interaction between phenobarbital and ciclosporin following renal transplantation : a case report

We report a case of decreased ciclosporin (CsA) trough level due to the interaction with phenobarbital after living renal transplantation in a 15-year-old male. Two other cases prescribed valproate sodium as an anticonvulsant, showed no change in the plasma CsA levels. Therefore, it is necessary to...

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Bibliographische Detailangaben
Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 36(1990), 4 vom: 01. Apr., Seite 447-50
1. Verfasser: Nishioka, T (VerfasserIn)
Weitere Verfasser: Ikegami, M, Imanishi, M, Ishii, T, Uemura, T, Kunikata, S, Kanda, H, Matsuura, T, Akiyama, T, Kurita, T
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1990
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:Case Reports English Abstract Journal Article Cyclosporins Phenobarbital YQE403BP4D
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520 |a We report a case of decreased ciclosporin (CsA) trough level due to the interaction with phenobarbital after living renal transplantation in a 15-year-old male. Two other cases prescribed valproate sodium as an anticonvulsant, showed no change in the plasma CsA levels. Therefore, it is necessary to recognize the drug interaction with CsA, and appropriate drug should be chosen in clinical renal transplantation 
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