Treatment using CDDP and radiation therapy in treating bladder tumor

Combination therapy consisting of cis-diamine-dichloroplatinum (CDDP) and radiotherapy was used to treat bladder cancer. The subjects were 20 patients with bladder cancer we experienced since September, 1986. They were between 33 and 83 years old and consisted of 13 males and 7 females. Among the hi...

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Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 36(1990), 7 vom: 14. Juli, Seite 765-70
1. Verfasser: Kase, T (VerfasserIn)
Weitere Verfasser: Kuwabara, T, Kuroda, K, Takanami, M, Yagishita, T, Sawamura, Y, Tajima, M, Matsushima, M, Shirai, M, Kaneko, I
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1990
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:English Abstract Journal Article Cisplatin Q20Q21Q62J
Beschreibung
Zusammenfassung:Combination therapy consisting of cis-diamine-dichloroplatinum (CDDP) and radiotherapy was used to treat bladder cancer. The subjects were 20 patients with bladder cancer we experienced since September, 1986. They were between 33 and 83 years old and consisted of 13 males and 7 females. Among the histotypes and grades, there were 3 cases of G2, 7 of G2-G3 and 10 of G3 metastatic epithelial carcinoma. The classification of primary tumors was T2 in six cases, T3a in 12 cases and T4 in two cases. In 12 cases where the bladder was preserved, this therapy was performed after TUR biopsy or TUR, and the effects were evaluated after observation periods of 5-17 months. Side effects caused by CDDP were anorexia in 15 cases, nausea and vomiting in 10 cases, leukopenia in 10 cases and thrombocytopenia in four cases. Those caused by the radiotherapy were diarrhea in seven cases and skin disorders in six cases. All of these side effects were mild and the patients recovered spontaneously
Beschreibung:Date Completed 07.12.1990
Date Revised 21.11.2013
published: Print
Citation Status MEDLINE
ISSN:0018-1994