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231221s1990 xx ||||| 00| ||jpn c |
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|a pubmed25n0070.xml
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|a (DE-627)NLM021040400
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|a (NLM)2122659
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a jpn
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| 100 |
1 |
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|a Kumamoto, Y
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Epidemiological and therapeutic study on urethritis of male and cervicitis from viewpoint of STD--a study using NY-198. Sapporo Clinical Research Group for STD
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| 264 |
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1 |
|c 1990
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 12.12.1990
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| 500 |
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|a Date Revised 09.12.2020
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| 500 |
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|a published: Print
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| 500 |
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|a Citation Status MEDLINE
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| 520 |
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|a Urethritis in males and cervicitis in females, which were sexually transmitted diseases, were treated with NY-198, a new quinolone antibiotic, and its efficacy was studied. Seventeen male patients with gonorrheal urethritis were administered a single 300 mg dose of NY-198. The efficacy rate on the 3rd day after administration was 100%, but it was 85.7% on the 7th day due to recurrence in 1 patient. The results of treatment of non-gonorrheal infections were as follow. In this treatment, NY-198 was administered in a daily dose of 600 mg in 3 divided doses for 14 consecutive days. In the treatment of chlamydial urethritis of males, the efficacy rate in 26 patients was 84.6% on the 7th day and 84.0% on the 14th day in 25 patients. In the treatment of chlamydial cervicitis, the efficacy rate was 100% on both the 7th (3/3) and 14th (6/6) days. In the treatment of non-gonorrheal and non-chlamydial cervicitis, the efficacy rate was 100% on the 7th day (1/1) and 50% (1/2) on 14th day. The efficacy rate in all 40 males with non-gonorrheal urethritis was 85.0% on the 7th day and 88.9% for 36 patients on the 14th day, while that in all 4 females with cervicitis was 100% on the 7th day and 87.5% on the 14th day. No side effects were seen in any of the patients. Overall, NY-198 had an efficacy rate of 80% in the treatment of chlamydial infections. NY-198 was found to be a useful drug which is efficacious in the treatment of all STD-related microbes such as gonococci and chlamydia
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| 650 |
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|a Clinical Trial
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| 650 |
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4 |
|a Journal Article
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| 650 |
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4 |
|a Multicenter Study
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| 650 |
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7 |
|a 4-Quinolones
|2 NLM
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| 650 |
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7 |
|a Anti-Infective Agents
|2 NLM
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| 650 |
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7 |
|a Fluoroquinolones
|2 NLM
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| 650 |
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7 |
|a Quinolones
|2 NLM
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| 650 |
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7 |
|a lomefloxacin
|2 NLM
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| 650 |
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7 |
|a L6BR2WJD8V
|2 NLM
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| 700 |
1 |
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|a Miyagishi, T
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Hirose, T
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Hayashi, K
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Gohro, T
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ueno, T
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Mohri, K
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kodama, N
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Abe, K
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Hinyokika kiyo. Acta urologica Japonica
|d 1962
|g 36(1990), 8 vom: 08. Aug., Seite 979-87
|w (DE-627)NLM012631779
|x 0018-1994
|7 nnas
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| 773 |
1 |
8 |
|g volume:36
|g year:1990
|g number:8
|g day:08
|g month:08
|g pages:979-87
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| 912 |
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|a GBV_USEFLAG_A
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| 912 |
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|a SYSFLAG_A
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| 912 |
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|a GBV_NLM
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| 912 |
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| 912 |
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|a GBV_ILN_2018
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| 951 |
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|a AR
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| 952 |
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|d 36
|j 1990
|e 8
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|h 979-87
|