Expression of transferrin receptor on transitional cell cancer

We examined the expression of transferrin receptor (TR) in transitional cell cancer (TCC) immunohistologically, to clarify its implication in tumor malignancy. Forty eight out of 51 tumors expressed TR while TR was not detected on the normal transitional epithelium of renal pelvis, ureter and urinar...

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Bibliographische Detailangaben
Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 37(1991), 1 vom: 11. Jan., Seite 11-6
1. Verfasser: Tomita, Y (VerfasserIn)
Weitere Verfasser: Nishiyama, T, Sato, S, Fujiwara, M
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1991
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:English Abstract Journal Article Receptors, Transferrin
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520 |a We examined the expression of transferrin receptor (TR) in transitional cell cancer (TCC) immunohistologically, to clarify its implication in tumor malignancy. Forty eight out of 51 tumors expressed TR while TR was not detected on the normal transitional epithelium of renal pelvis, ureter and urinary bladder. In general, a higher grade and more invasive TCC expressed TR more frequently and more intensely. Furthermore, recurrent tumors treated with transurethral resection significantly more frequently expressed TR than the initial tumor. These results indicate that the detection of TR on the tumor cells is useful for estimating the degree of their malignancy 
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