Clinical evaluation of serum basic fetoprotein in patients with urogenital malignancies and renal transplantation

The serum basic fetoprotein (BFP) in patients with urogenital diseases was measured by enzyme immunoassay (EIA). The positive range of serum BFP was defined to be 75 ng/ml or more. In benign cases except for renal transplantation, the positive rate of serum BFP was 11.1% (5/45), and relatively high...

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Bibliographische Detailangaben
Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 37(1991), 11 vom: 25. Nov., Seite 1475-9
1. Verfasser: Seguchi, T (VerfasserIn)
Weitere Verfasser: Sugao, H, Takahara, S, Nakano, E, Ishibashi, M, Sonoda, T
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1991
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:English Abstract Journal Article alpha-Fetoproteins
Beschreibung
Zusammenfassung:The serum basic fetoprotein (BFP) in patients with urogenital diseases was measured by enzyme immunoassay (EIA). The positive range of serum BFP was defined to be 75 ng/ml or more. In benign cases except for renal transplantation, the positive rate of serum BFP was 11.1% (5/45), and relatively high (21.4%, 3/14) in benign prostatic hypertrophy. In cases of urogenital cancers before treatment, the positive rate of serum BFP was 29.1% (16/55), and increased with the progression of clinical stage. Eleven of the patients with positive serum BFP before treatment were re-examined after treatment, and all of them exhibited a marked decrease of the titer of serum BFP. In seventeen renal transplant patients, the positive rate of serum BFP was 100% (8/8) in acute rejection, 66.7% (2/3) in chronic rejection and 0% (0/6) in rejection-free condition. We conclude that serum BFP is a clinically beneficial marker for renal transplant rejections and urogenital malignancies
Beschreibung:Date Completed 19.02.1992
Date Revised 15.11.2006
published: Print
Citation Status MEDLINE
ISSN:0018-1994