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NLM015911519 |
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tu |
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231221s1992 xx ||||| 00| ||jpn c |
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|a jpn
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| 100 |
1 |
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|a Yamashita, S
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Postoperative adjuvant M-VAC chemotherapy for invasive bladder cancer
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| 264 |
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1 |
|c 1992
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 17.07.1992
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| 500 |
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|a Date Revised 21.11.2013
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| 500 |
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|a published: Print
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|a Citation Status MEDLINE
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| 520 |
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|a Between 1986 and 1989, 14 patients undergoing cystectomy for bladder cancer, in pathological stage high risk pT2 group, pT3-4 and/or with N+ disease, received postoperative adjuvant methotrexate, vinblastine, doxorubicin and cisplatin (M-VAC) chemotherapy. Of the 14 patients 10 were alive with no evidence of disease for an average of 41 months. Tumor recurrence was seen in 4 patients (bone in 2, lungs in 1, brain in 1 patient). Of the 4 patients, 3 patients died of cancer progression at an average of 26 months and 1 patient was alive with tumor for 30 months. Their actual survival rate at 64 months was 70%, which was significantly higher than that of the historical control groups (1974-1981: 18%, 1982-1985: 46%). Although postoperative adjuvant M-VAC chemotherapy for invasive bladder cancer seemed effective in this study, a controlled randomized study will be necessary to conclude if it could be of real benefit for these patients
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| 650 |
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|a English Abstract
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4 |
|a Journal Article
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| 650 |
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7 |
|a Vinblastine
|2 NLM
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| 650 |
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7 |
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|2 NLM
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7 |
|a Doxorubicin
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| 650 |
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7 |
|a 80168379AG
|2 NLM
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| 650 |
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7 |
|a Cisplatin
|2 NLM
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| 650 |
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7 |
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|2 NLM
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| 650 |
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7 |
|a Methotrexate
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| 650 |
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1 |
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|e verfasserin
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| 700 |
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|a Saito, Y
|e verfasserin
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| 700 |
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|a Yushita, Y
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| 700 |
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|a Sakuragi, T
|e verfasserin
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| 773 |
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|i Enthalten in
|t Hinyokika kiyo. Acta urologica Japonica
|d 1962
|g 38(1992), 5 vom: 09. Mai, Seite 519-24
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|x 0018-1994
|7 nnns
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|g volume:38
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