Recombinant circle PCR and recombination PCR for site-specific mutagenesis without PCR product purification

Two simple methods for site-specific mutagenesis are described and compared. In each method, the PCR is used in two separate amplifications to mutate the site of interest and to add ends to one PCR product that are homologous to the ends of the other PCR product. In the first method, the two product...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:BioTechniques. - 1991. - 12(1992), 4 vom: 15. Apr., Seite 528-30, 532, 534-5
1. Verfasser: Jones, D H (VerfasserIn)
Weitere Verfasser: Winistorfer, S C
Format: Aufsatz
Sprache:English
Veröffentlicht: 1992
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Comparative Study Journal Article Research Support, Non-U.S. Gov't DNA Probes