Molecular AFM imaging of Hsp70-1A association with dipalmitoyl phosphatidylserine reveals membrane blebbing in the presence of cholesterol

Hsp70-1A—the major stress-inducible member of the HSP70 chaperone family—is being implicated in cancer diseases with the development of resistances to standard therapies. In normal cells, the protein is purely cytosolic, but in a growing number of tumor cells, a significant fraction can be identifie...

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Veröffentlicht in:Cell Stress & Chaperones. - Elsevier. - 23(2018), 4, Seite 673-683
1. Verfasser: Lamprecht, Constanze (VerfasserIn)
Weitere Verfasser: Gehrmann, Mathias, Madl, Josef, Römer, Winfried, Multhoff, Gabriele, Ebner, Andreas
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:Cell Stress & Chaperones
Schlagworte:Physical sciences Biological sciences Health sciences Applied sciences