Ancient DNA Investigation of a Medieval German Cemetery Confirms Long-Term Stability of CCR5-Δ32 Allele Frequencies in Central Europe

The CCR5-Δ32 mutation present in European populations is among the most prominently debated cases of recent positive selection in humans. This allele, a 32-bp deletion that renders the T-cell CCR5 receptor nonfunctional, has important epidemiological and public health significance, as homozygous car...

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Veröffentlicht in:Merrill-Palmer Quarterly. - Wayne State University Press, 1982. - 89(2017), 2, Seite 119-124
Format: Online-Aufsatz
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Merrill-Palmer Quarterly
Schlagworte:ANCIENT DNA CCR5 MEDIEVAL Biological sciences Physical sciences Health sciences