The Genomic Health of Ancient Hominins
The genomes of ancient humans, Neandertals, and Denisovans contain many alleles that influence disease risks. Using genotypes at 3,180 disease-associated loci, we estimated the disease burden of 147 ancient genomes. After correcting for missing data, genetic risk scores (GRS) were generated for nine...
| Format: | Online-Aufsatz |
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| Veröffentlicht: |
2017
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| Schlagworte: | ANCIENT DNA GENETIC DISEASE RISKS HUMAN EVOLUTION POPULATION GENETICS PREDICTIVE HEALTH Health sciences Biological sciences |