Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak

Antiapoptotic B-cell lymphoma 2 (Bcl-2) family members such as Bcl-2, myeloid cell leukemia 1 (Mcl-1), and B-cell lymphoma-X large (Bcl-xL) are proposed to inhibit autophagy by directly binding to the BH3 domain of Beclin 1/Atg6. However, these Bcl-2 family pro...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences of the United States of America. - National Academy of Sciences of the United States of America. - 111(2014), 23, Seite 8512-8517
1. Verfasser:	Lindqvist, Lisa M. (VerfasserIn)
Weitere Verfasser:	Heinlein, Melanie, Huang, David C. S., Vaux, David L.
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2014
Zugriff auf das übergeordnete Werk:	Proceedings of the National Academy of Sciences of the United States of America
Schlagworte:	Biological sciences Behavioral sciences Health sciences