Essential Role of BDNF in the Mesolimbic Dopamine Pathway in Social Defeat Stress

Mice experiencing repeated aggression develop a long-lasting aversion to social contact, which can be normalized by chronic, but not acute, administration of antidepressant. Using viralmediated, mesolimbic dopamine pathway-specific knockdown of brain-derived neurotrophic factor (BDNF), we showed tha...

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Veröffentlicht in:Science. in. - The American Association for the Advancement of Science, 1880. - 311(2006), 5762, Seite 864-868
1. Verfasser: Berton, Olivier (VerfasserIn)
Weitere Verfasser: McClung, Colleen A., DiLeone, Ralph J., Krishnan, Vaishnav, Renthal, William, Russo, Scott J., Graham, Danielle, Tsankova, Nadia M., Bolanos, Carlos A., Rios, Maribel, Monteggia, Lisa M., Self, David W., Nestler, Eric J.
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2006
Zugriff auf das übergeordnete Werk:Science. in
Schlagworte:Biological sciences Behavioral sciences Health sciences