An Acutely and Latently Expressed Herpes Simplex Virus 2 Viral microRNA Inhibits Expression of ICP34.5, a Viral Neurovirulence Factor

Latency-associated transcript (LAT) sequences regulate herpes simplex virus (HSV) latency and reactivation from sensory neurons. We found a HSV-2 LAT-related microRNA (miRNA) designated miR-I in transfected and infected cells in vitro and in acutely and latently infected ganglia of guinea pigs in vi...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences of the United States of America. - National Academy of Sciences of the United States of America. - 105(2008), 31, Seite 10931-10936
1. Verfasser:	Tang, Shuang (VerfasserIn)
Weitere Verfasser:	Bertke, Andrea S., Patel, Amita, Wang, Kening, Cohen, Jeffrey I., Krause, Philip R.
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2008
Zugriff auf das übergeordnete Werk:	Proceedings of the National Academy of Sciences of the United States of America
Schlagworte:	HSV Latency-associated transcript Latency Reactivation Human Biological sciences Physical sciences Health sciences Applied sciences