Nucleophosmin Interacts Directly with c-Myc and Controls c-Myc-Induced Hyperproliferation and Transformation

The transcription factor c-Myc is essential for cellular proliferation and is one of the most frequently activated oncogenes, but the molecular mechanism mediating its critical role in transformation is unclear. Like c-Myc, multifunctional nucleophosmin (NPM) is tightly regulated during proliferatio...

Ausführliche Beschreibung

Bibliographische Detailangaben

1. Verfasser:	Li, Zhaoliang (VerfasserIn)
Weitere Verfasser:	Boone, David, Hann, Stephen R.
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2008
Schlagworte:	Myc Proliferation NPM B23 Biological sciences Physical sciences Health sciences