Efficacy, renal safety and tolerability of sodium-glucose cotransporter 2 inhibitors (SGLT2i) in elderly patients with type 2 diabetes: A real-world experience

• Older patients with T2DM are often excluded from randomized controlled trials. • The insulin-independent mechanism of action makes SGLT2i suitable in the elderly. • Our study focused on SGLT2i-treated older patients with T2DM, stratified by age (65–69 and ≥70 years). • HbA1c reduction, eGFR variat...

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Bibliographische Detailangaben
Veröffentlicht in:A pilot randomized controlled trial examining the feasibility, acceptability, and efficacy of Adapted Motivational Interviewing for post-operative bariatric surgery patients. - 2016. - Amsterdam [u.a.]
1. Verfasser: Tumminia, Andrea (VerfasserIn)
Weitere Verfasser: Graziano, Marco (BerichterstatterIn), Vinciguerra, Federica (BerichterstatterIn), Lomonaco, Andrea (BerichterstatterIn), Frittita, Lucia (BerichterstatterIn)
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:A pilot randomized controlled trial examining the feasibility, acceptability, and efficacy of Adapted Motivational Interviewing for post-operative bariatric surgery patients
Schlagworte:Type 2 diabetes Elderly Sodium-glucose cotransporter 2 inhibitors Real-world evidence
Umfang:6
Beschreibung
Zusammenfassung:• Older patients with T2DM are often excluded from randomized controlled trials. • The insulin-independent mechanism of action makes SGLT2i suitable in the elderly. • Our study focused on SGLT2i-treated older patients with T2DM, stratified by age (65–69 and ≥70 years). • HbA1c reduction, eGFR variation and tolerability were similar across age groups. • Among elderly T2DM individuals, SGLT2i are effective, safe and fairly well tolerated.
Beschreibung:6
DOI:10.1016/j.pcd.2020.10.002