Reference intervals of citrated-native whole blood thromboelastography in premature neonates

Bleeding due to acquired coagulation disorders is a common complication in premature neonates. In this clinical setting, standard coagulation laboratory tests might be unsuitable to investigate the hemostatic function as they reflect the concentration of pro-coagulant proteins but not of anti-coagul...

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Veröffentlicht in:Study of serum leptin in well differentiated thyroid carcinoma: Correlation with patient and tumor characteristics. - 2014. - Amsterdam [u.a.]
1. Verfasser: Motta, Mario (VerfasserIn)
Weitere Verfasser: Guaragni, Brunetta (BerichterstatterIn), Pezzotti, Elena (BerichterstatterIn), Rodriguez-Perez, Carmen (BerichterstatterIn), Chirico, Gaetano (BerichterstatterIn)
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017transfer abstract
Zugriff auf das übergeordnete Werk:Study of serum leptin in well differentiated thyroid carcinoma: Correlation with patient and tumor characteristics
Umfang:4
Beschreibung
Zusammenfassung:Bleeding due to acquired coagulation disorders is a common complication in premature neonates. In this clinical setting, standard coagulation laboratory tests might be unsuitable to investigate the hemostatic function as they reflect the concentration of pro-coagulant proteins but not of anti-coagulant proteins. Thromboelastography (TEG), providing a more complete assessment of hemostasis, may be able to overcome some of these limitations. Unfortunately, experience on the use of TEG in premature neonates is very limited and, in particular in this population, reference ranges of TEG parameters have not been yet evaluated.
Bleeding due to acquired coagulation disorders is a common complication in premature neonates. In this clinical setting, standard coagulation laboratory tests might be unsuitable to investigate the hemostatic function as they reflect the concentration of pro-coagulant proteins but not of anti-coagulant proteins. Thromboelastography (TEG), providing a more complete assessment of hemostasis, may be able to overcome some of these limitations. Unfortunately, experience on the use of TEG in premature neonates is very limited and, in particular in this population, reference ranges of TEG parameters have not been yet evaluated.
Beschreibung:4
DOI:10.1016/j.earlhumdev.2017.09.014