Timing of autophagy and apoptosis during posterior silk gland degeneration in <ce:italic>Bombyx mori</ce:italic>

Timing of autophagy and apoptosis during posterior silk gland degeneration in <ce:italic>Bombyx mori</ce:italic>

Over the years, the silkworm, Bombyx mori, has been manipulated by means of chemical and genetic approaches to improve silk production both quantitatively and qualitatively. The silk is produced by the silk gland, which degenerates quickly once the larva has finished spinning the cocoon. Thus, inter...

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Veröffentlicht in:Ventricular Restraint Improves Outcomes in HF Patients with CRT. - 2011. - Amsterdam [u.a.]
1. Verfasser: Montali, Aurora (VerfasserIn)
Weitere Verfasser: Romanelli, Davide (BerichterstatterIn), Cappellozza, Silvia (BerichterstatterIn), Grimaldi, Annalisa (BerichterstatterIn), de Eguileor, Magda (BerichterstatterIn), Tettamanti, Gianluca (BerichterstatterIn)
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017transfer abstract
Zugriff auf das übergeordnete Werk:Ventricular Restraint Improves Outcomes in HF Patients with CRT
Schlagworte:Silk gland <ce:italic>Bombyx mori</ce:italic> Programmed cell death Autophagy Metamorphosis Apoptosis
Umfang:11
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520 |a Over the years, the silkworm, Bombyx mori, has been manipulated by means of chemical and genetic approaches to improve silk production both quantitatively and qualitatively. The silk is produced by the silk gland, which degenerates quickly once the larva has finished spinning the cocoon. Thus, interfering with this degeneration process could help develop new technologies aimed at ameliorating silk yield. To this end, in this work we studied the cell death processes that lead to the demise of the posterior silk gland of B. mori, directing in particular our attention to autophagy and apoptosis. We focused on this portion of the gland because it produces fibroin, the main component of the silk thread. By using multiple markers, we provide a morphological, biochemical and molecular characterization of the apoptotic and autophagic processes and define their timing in this biological setting. 
520 |a Over the years, the silkworm, Bombyx mori, has been manipulated by means of chemical and genetic approaches to improve silk production both quantitatively and qualitatively. The silk is produced by the silk gland, which degenerates quickly once the larva has finished spinning the cocoon. Thus, interfering with this degeneration process could help develop new technologies aimed at ameliorating silk yield. To this end, in this work we studied the cell death processes that lead to the demise of the posterior silk gland of B. mori, directing in particular our attention to autophagy and apoptosis. We focused on this portion of the gland because it produces fibroin, the main component of the silk thread. By using multiple markers, we provide a morphological, biochemical and molecular characterization of the apoptotic and autophagic processes and define their timing in this biological setting. 
650 7 |a Silk gland  |2 Elsevier 
650 7 |a <ce:italic>Bombyx mori</ce:italic>  |2 Elsevier 
650 7 |a Programmed cell death  |2 Elsevier 
650 7 |a Autophagy  |2 Elsevier 
650 7 |a Metamorphosis  |2 Elsevier 
650 7 |a Apoptosis  |2 Elsevier 
700 1 |a Romanelli, Davide  |4 oth 
700 1 |a Cappellozza, Silvia  |4 oth 
700 1 |a Grimaldi, Annalisa  |4 oth 
700 1 |a de Eguileor, Magda  |4 oth 
700 1 |a Tettamanti, Gianluca  |4 oth 
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