Possible alternatives to antimicrobial therapies
The care of immunosuppressed patients has constantly improved over the years, and pharmacologic developments contributed significantly to this success. However, despite these advances, current anti-infectious agents are limited in their efficacy by either weak specificity or side effects, including...
| Publié dans: | Study of serum leptin in well differentiated thyroid carcinoma: Correlation with patient and tumor characteristics. - 2014. - Amsterdam [u.a.] |
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| Auteur principal: | |
| Autres auteurs: | , , |
| Format: | Article en ligne |
| Langue: | English |
| Publié: |
2014transfer abstract
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| Accès à la collection: | Study of serum leptin in well differentiated thyroid carcinoma: Correlation with patient and tumor characteristics |
| Sujets: | T cell therapy Transplantation Fungal infections Viral infections |
| Description matérielle: | 3 |
| Résumé: | The care of immunosuppressed patients has constantly improved over the years, and pharmacologic developments contributed significantly to this success. However, despite these advances, current anti-infectious agents are limited in their efficacy by either weak specificity or side effects, including suppression of bone marrow function. Control of infection will ultimately depend on reconstitution of specific immunity. Thus, adoptive cellular immunotherapy represents an attractive, low-toxicity strategy to restore specific immune surveillance, and prevent/treat potentially life-threatening disease due to pathogens relevant to the immunosuppressed host. The care of immunosuppressed patients has constantly improved over the years, and pharmacologic developments contributed significantly to this success. However, despite these advances, current anti-infectious agents are limited in their efficacy by either weak specificity or side effects, including suppression of bone marrow function. Control of infection will ultimately depend on reconstitution of specific immunity. Thus, adoptive cellular immunotherapy represents an attractive, low-toxicity strategy to restore specific immune surveillance, and prevent/treat potentially life-threatening disease due to pathogens relevant to the immunosuppressed host. |
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| Description matérielle: | 3 |
| DOI: | 10.1016/S0378-3782(14)70006-4 |